Present – 2020
Nauman MC, Johnson JJ. The purple mangosteen (Garcinia mangostana): Defining the anticancer potential of selected xanthones. Pharmacol Res. 2021 Dec 9:106032. doi: 10.1016/j.phrs.2021.106032. PMID: 34896543
Vemu B, Tocmo R, Nauman MC, Flowers SA, Veenstra JP, Johnson JJ*.
Pharmacokinetic characterization of carnosol from rosemary (Salvia Rosmarinus) in male C57BL/6 mice and inhibition profile in human cytochrome P450 enzymes. Toxicol Appl Pharmacol. 2021. 15;431:115729. doi: 10.1016/j.taap.2021.115729.
Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ*. Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells. Nutrients. 2021;13(9):3156. doi: 10.3390/nu13093156.
Veenstra JP, Johnson JJ*. Rosemary (Salvia rosmarinus): Health-Promoting Benefits and Food Preservative Properties. Int J Nutr. 2021;6(4):1-10.
Gaba RC, Khabbaz RC, Muchiri RN, Morrison JD, Elkhadragy L, Totura WM, Samuelson JP, Whiteley HE, Deaton RL, Nguyen PL, Sverdlov M, Johnson JJ, van Breemen RB, Lokken RP. Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model. Drug Deliv Transl Res. 2021. doi: 10.1007/s13346-021-00985-8.
Bailey HH, Johnson JJ, Lozar T, Scarlett CO, Wollmer BW, Kim K, Havinghurst T, Ahmad N. A randomized, double-blind, dose-ranging, pilot trial of piperine with resveratrol on the effects on serum levels of resveratrol. Eur J Cancer Prev. 2021;30(3):285-290. doi: 10.1097/CEJ.0000000000000621.
Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ*. Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis. Nutrients. 2021 Feb 27;13(3):773. doi: 10.3390/nu13030773.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ*. Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells. Free Radic Biol Med. 2021;163:102-115. doi: 10.1016/j.freeradbiomed.2020.11.018.
Tocmo R, Veenstra JP, Huang Y, Johnson JJ*. Covalent modification of proteins byplant-derived natural products: Proteomics approaches and biological impacts. Proteomics. 2021;21(3-4):e1900386. doi: 10.1002/pmic.201900386.
Nauman MC, Tocmo R, Vemu B, Veenstra JP, Johnson JJ*. Inhibition of CDK2/CyclinE1 by xanthones from the mangosteen (Garcinia mangostana): A structure-activity relationship study. Natural Products Research. 2020. 21;1-5.
Tocmo R, Pena-Fronteras J, Calumba KF, Mendoza M, Johnson JJ*. Valorization of pomelo (Citrus grandis Osbeck) peel: A review of current utilization, phytochemistry, bioactivities and mechanisms of action. Comprehensive Reviews in Food Science and Food Safety. 2020; 19 (4): 1969-2012
Sweiss K, Vemu B, Calip GS, Wenzler E, Galvin JP, Mahmud N, Rondelli D, Johnson JJ*, Patel P. Development of a Method for Clinical Pharmacokinetic Testing to Allow for Targeted Melphalan Dosing in Multiple Myeloma Patients Undergoing Autologous Transplant. British Journal of Clinical Pharmacology. 2020 86(11):2165-2173. doi: 10.1111/bcp.14308.
2019 – 2015
Vemu B, Nauman MC, Veenstra JP, Johnson JJ*. Structure activity relationship of xanthones from mangosteen (Garcinia mangostana) for inhibition of Cyclin Dependent Kinase 4. International Journal of Nutrition. 2019;4(2):38-45.
Sweiss K, Calip GS, Johnson JJ, Rondelli D, Patel PR. Pre-transplant hemoglobin and creatinine clearance correlate with treatment free survival after autologous stem cell transplantation for multiple myeloma. Bone Marrow Transplant. 2019;54(12):2081-2087
Veenstra JP, Johnson JJ*. Oregano (Origanum vulgare) extract for food preservation and improvement in gastrointestinal health. International Journal of Nutrition. 2019;3(4):43-52
Nauman MC, Johnson JJ*. Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integrative Food, Nutrition, and Metabolism. 2019; 6 (2):v1-7.
Yan M, Vemu B, Veenstra J, Petiwala SM, Johnson JJ*. Carnosol, a dietary diterpene from rosemary (Rosmarinus officinalis) activates Nrf2 leading to sestrin 2 induction in colon cells. Integrative Molecular Nutrition. 2018; 5 (4): 1-7
Petiwala SM, Li G, Petukhov P, Johnson JJ*. Carnosic acid promotes degradation of the androgen receptor and is regulated by the unfolded protein response pathway in vitro and in vivo. Carcinogenesis. 2016; 37 (8):827-38. PMID: 27267997
Li G, Petiwala SM, Yan M, Petukhov P, Johnson JJ*. Gartanin, an isoprenylated xanthone from Garcinia mangostana, is an androgen receptor degradation enhancer in prostate cancer cells. Molecular Nutrition and Food Research. 2016; 60(6):1458-69. PMID: 27019217
Petiwala SM, Johnson JJ*. Diterpenes from rosemary (Rosmarinus officinalis): Defining their potential for anti-cancer activity. Cancer Letters. 2015. 367(2):93-102 PMID: 26170168
Yan M, Li G, Petiwala SM, Johnson JJ*. Standardized rosemary (Rosmarinus officinalis) extract induces Nrf2/sestrin-2 pathway in colon cancer cells. Journal of Functional Foods. 2015. 13:137-147
2014 – 2010
Li G, Petiwala SM, Nonn L, Johnson JJ*. Inhibition of CHOP accentuates the apoptotic effect of α-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells. Biochemistry and Biophysics Research Communication. 2014 ;453(1):75-80. PMID: 25261723
Ng V, Johnson JJ, Puri SC. Targeting the mTOR pathway with everolimus: implications for the management of metastatic breast cancer. Journal of Oncology Pharmacy Practice. J Oncol Pharm Pract. 2014. PMID: 24964967
Petiwala SM, Li G, Ramaiya A, Kumar A, Gill RK, Saksena S, Johnson JJ*. Pharmacokinetic characterization of mangosteen (Garcinia mangostana) fruit extract standardized to α-mangostinin C57BL/6 mice. Nutrition Research. 2014;34(4):336-45. PMID: 24774070
Petiwala SM, Berhe S, Li G, Puthenveetil AG, Rahman O, Nonn L, Johnson JJ*. Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth. PLOS One. 2014 Mar 5;9(3):e89772. PMID: 24598693
Gongbo L, Petiwala SM, Pierce DM, Nonn L, Johnson JJ*. Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract. PLOS One 2013 Dec 18;8(12):e81572
Siddique H, Adhami VM, Parray A, Johnson JJ, Siddiqui IA, Shekhani MT, Murtaza I, Amartsumian N, Konety BR, Mukhtar H, Saleem M. S100A4 Promotes Prostate Tumorigenesis through the Activation of RAGE/NFkappaB Circuitry: Studies in Tumor cells, Human Patients and Transgenic Mouse Model. Genes Cancer. 2013; 4(5-6): 224-34.
Gongbo Li, Thomas SP, Johnson JJ*. Polyphenols from the mangosteen (Garcinia mangostana) fruit for prostate and breast cancer. Frontiers in Pharmacology. 2013;4:80. PMID: 23805102
Petiwala SM, Puthenveetil AG, Johnson JJ*. Polyphenols from the Mediterranean herb rosemary (Rosmarinus officinalis) for prostate cancer. Frontiers in Pharmacology. 2013; 4:29. PMID: 23531917
Ramaiya A, Li G, Petiwala SM, Johnson JJ*. Single dose oral pharmacokinetic profile of α- mangostin in mice. Current Drug Targets. 2012; 13: 1698-704. PMID: 23140281
Johnson JJ*, Syed DS, Rasmussen JT, Adhami V, Siddiqui IA, Kohl A, Mukhtar H. α-Mangostin, a xanthone from mangosteen fruit, inhibits CDK4 leading to G1 cell cycle arrest in prostate cancer and decreases xenograft tumor growth. Carcinogenesis. 2012; 33(2):413-9. PMID: 22159229
Johnson JJ*, Minakshi N, Siddiqui IA, Scarlett CO, Bailey HH, Muktar H, Ahmad, N. Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular Nutrition and Food Research. 2011; 55(8):1169-76. PMID: 21714124
Johnson JJ*. Carnosol: a promising anti-cancer agent. Cancer Letters. 2011; 305(1):1-7. PMID: 21382660
Syed DN, Afaq F, Maddodi N, Johnson JJ, Sarafaz S, Ahmad A, Setaluri V, Mukhtar H. Inhibition of human melanoma cell growth by dietary flavonoid fisetin is associated with disruption of Wnt/β- catenin signaling and decreased Mitf levels. Journal of Investigative Dermatology. 2011;131(6):1291-9. PMID: 21346776
Johnson JJ*, Syed DS, Suh Y, Heren CR, Saleem M, Siddiqui IA, Mukhtar H. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention. Cancer Prevention Research. 2010;3:1112-23. PMID: 20736335
Suh Y, Afaq F, Khan N, Johnson JJ, Khusro FH, Mukhtar H. Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. Carcinogenesis. 2010 Jun 8. PMID: 20530556
Johnson JJ*, Bailey H, Mukhtar H. Green tea polyphenols for prostate cancer chemoprevention: A translational perspective. Phytomedicine. 2010;17:3-13. PMID: 19959000
2009 – 2006
Saleem M, Murtaza I, Tarapore R, Suh Y, Adhami VM, Johnson JJ, Siddiqui IA, Khan N, Asim M, Hafeez BB, Shekhani MT, Li B, Mukhtar H. Lupeol Inhibits Proliferation of Human Prostate Cancer Cells by Targeting Growth Factor Receptor /β-catenin Signaling Network. Carcinogenesis. 2009;30: 808-17. PMID: 19233958
Suh Y, Afaq F, Johnson JJ, Mukhtar H. A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-κB signaling pathways. Carcinogenesis. 2009; 30: 300-7. PMID: 19037088
Johnson JJ*, Syed DN, Heren CR, Suh Y, Adhami VM, Mukhtar H. Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5′-AMP-activated protein kinase (AMPK) pathway. Pharmaceutical Research. 2008. 25: 2125-34. PMID: 18286356
Saleem M, Kweon MH, Johnson JJ, Adhami VM, Elcheva I, Khan N, Bin Hafeez B, Bhat KM, Sarfaraz S, Reagan-Shaw S, Spiegelman VS, Setaluri V, Mukhtar H. S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9. Proceedings of the National Academy of Sciences USA. 2006;103:14825-30. PMID: 16990429
Pomplun M, Johnson JJ, Johnston S, Kolesar JM. Stability of a heparin-free 50% ethanol lock solution for central venous catheters. Journal of Oncology Pharmacy Practice. 2007;13:33-7. PMID: 17621565
Johnson JJ*, Mukhtar H. Curcumin for chemoprevention of colon cancer. Cancer Letters. 2007; 255(2):170-81. PMID: 17448598