Can rosemary extract be beneficial for colitis? – New Paper

by Dr. Jeremy Johnson | Posted on

In a recent paper we describe how rosemary extract, an approved food preservative in the European Union, has the potential to treat colitis in a preclinical model.  

Interestingly, we found that the extract was able to target Sestrin-2 which has been reported to be overexpressed in a colitis model. 

In addition, we also analyzed the pharmacokinetic properties of carnosic acid and carnosol in mice.

Our results suggest that these phytochemicals were well absorbed after oral administration.

This study suggests that rosemary may be an effective preventative agent against irritable bowel disease.

This paper was published in the journal Nutrients and is titled, “ Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.”

You can read it here https://pubmed.ncbi.nlm.nih.gov/33673488/

About the author

Dr. Johnson received his PharmD and PhD at the University of Wisconsin where he also completed a clinical research fellowship evaluating phytochemicals and botanical extracts. He is an associate professor and licensed pharmacist he offers a unique perspective on the most current scientific literature related to the health and nutrition. His research program is active and has led to more than 50 publications and published abstracts related to the health promoting properties of natural products, phytochemicals and plant extracts. He has presented some of his research findings at international scientific meetings in the US, Italy, Austria, Israel, France, China, Philippines and Turkey.

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